1.
Emerg Infect Dis
; 27(9): 2499-2501, 2021 Sep.
Article
in English
| MEDLINE | ID: covidwho-1435937
ABSTRACT
We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.
Subject(s)
COVID-19 , SARS-CoV-2 , Evolution, Molecular , Genomics , Humans , Immunocompromised Host , Ireland
2.
Respir Med
; 185: 106481, 2021.
Article
in English
| MEDLINE | ID: covidwho-1253572
ABSTRACT
Non-invasive respiratory support (NRS) outside of the ICU has played an important role in the management of COVID-19 pneumonia. There is little data to guide selection of NRS modality. We present outcomes of NRS outside the ICU and discuss the effects of NRS on gas exchange with implications for management.